GABAB R2/GABBR2 Purified抗体

产品货号：

Z37706

中文名称：

GABAB R2/GABBR2 Purified抗体

英文名称：

Anti-GABAB R2/GABBR2 Purified Antibody (Clone#PAb (551))

产品规格：

0.1mg(C100)

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-GABAB R2/GABBR2 Purified Antibody (Clone#PAb (551))
指标别名	Gamma-aminobutyric acid type B receptor subunit 2;GABA-B receptor 2;GABA-B-R2;GABA-BR2;GABABR2;Gb2;G-protein coupled receptor 51;Gabbr2;Gm425;Gpr51
克隆性	Monoclonal
检验物种	rat,mouse
应用范围	WB,ICC
基因名称	GABBR2
克隆号	PAb (551)
抗体来源	Rabbit
抗体类型	IgG
免疫原	Synthetic peptide (coupled with THG) derived from the last 23 aa of mouse GABA B receptor 2.100% homology with human GB2.The polyclonal antibody recognizes C-terminus of gamma-aminobutyric acid (GABA) B receptor 2 (recognized epitope:the last 23 aa).GB2 apparent MW~120kDa.
计算分子量	106kDa
成分	Phosphate buffered saline (PBS),pH7.4,15mM sodium azide
纯化方式	Purified by ligand affinity chromatography.
浓度	1mg/mL
产品形态	溶液
保存条件	Store at 2～8℃.Do not freeze.
背景资料	GABA B receptor is a G-protein-coupled inhibitory receptor of gamma-aminobutyric acid (GABA),and has important functions in brain by inhibition of adenylyl cyclase and modulation of G-protein-gated Ca²⁺ and K⁺ channels.GABA B receptor is comprised of two subunits,GB1 and GB2 with N-terminal extracellular and C-terminal intracellular domains.The GB1 subunit plays a critical role in ligand binding,whereas the GB2 subunit contains the determinants required for G-protein signaling.Multiple allosteric interactions between the two subunits are required for correct functioning of the receptor.There are two N-terminal splice variants of GB1 subunit,termed GB1a and GB1b;their expression in the central nervous system changes during the ontogenesis and differs between various regions of the brain.
Uniprot ID	O88871
基因名全称	Gamma-aminobutyric acid type B receptor subunit 2
蛋白名全称	Gamma-aminobutyric acid type B receptor subunit 2
推荐稀释比	Western blotting:0.6μg/mL.

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